Shares of biotech companies fell after US Democratic presidential candidate Hillary Clinton said she would announce a plan to stop "price gouging" for specialty drugs.
Biogen fell 5.6 percent to USD 297.16 and Gilead was down 2.5 percent at USD 105.74. The S&P healthcare sector fell 1.4 percent and was the only S&P 500 sector index to end lower.
The Nasdaq biotech index slumped 4.4 percent.
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